Depressive symptom profile in Parkinson's disease: a comparison with depression in elderly patients without Parkinson's disease
Identifieur interne : 001B24 ( Main/Corpus ); précédent : 001B23; suivant : 001B25Depressive symptom profile in Parkinson's disease: a comparison with depression in elderly patients without Parkinson's disease
Auteurs : Uwe Ehrt ; Kolbj Rn Br Nnick ; Albert F. G. Leentjens ; Jan Petter Larsen ; Dag AarslandSource :
- International Journal of Geriatric Psychiatry [ 0885-6230 ] ; 2006-03.
English descriptors
Abstract
Objective: Depression is a common neuropsychiatric syndrome in Parkinson's disease (PD), and may be etiologically related to the neurochemical changes accompanying this disease. It is still unclear whether the disturbances of neurotransmitter activities lead to a specific profile of depressive symptoms, that is characteristic for PD and differs from that in depressed patients without PD. Method: We compared the individual depressive symptoms of 145 non‐demented depressed patients with PD and 100 depressed patients without PD by comparing item scores on the Montgomery‐Åsberg Depression Rating Scale by way of MANCOVA. Results: The severity of depression and the level of cognitive functioning in depressed PD patients were comparable with that of depressed control subjects. However, patients with PD showed significant less reported sadness, less anhedonia, less feelings of guilt and, slightly less loss of energy, but more concentration problems than depressed control subjects. Conclusion: The profile of depressive symptoms in PD differs from that in depressed subjects without PD. This finding is important for the conceptualisation and clinical diagnosis of depression in PD. Copyright © 2006 John Wiley & Sons, Ltd.
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DOI: 10.1002/gps.1456
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ISTEX:CB8596FF1264CC9706FA7D3D3FCEFAB7189DAA55Le document en format XML
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J. Geriat. Psychiatry</title><idno type="ISSN">0885-6230</idno><idno type="eISSN">1099-1166</idno><imprint><publisher>John Wiley & Sons, Ltd.</publisher><pubPlace>Chichester, UK</pubPlace><date type="published" when="2006-03">2006-03</date><biblScope unit="volume">21</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="252">252</biblScope><biblScope unit="page" to="258">258</biblScope></imprint><idno type="ISSN">0885-6230</idno></series><idno type="istex">CB8596FF1264CC9706FA7D3D3FCEFAB7189DAA55</idno><idno type="DOI">10.1002/gps.1456</idno><idno type="ArticleID">GPS1456</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-6230</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson's disease</term><term>depression</term><term>neuropsychiatry</term><term>symptom profile</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Objective: Depression is a common neuropsychiatric syndrome in Parkinson's disease (PD), and may be etiologically related to the neurochemical changes accompanying this disease. It is still unclear whether the disturbances of neurotransmitter activities lead to a specific profile of depressive symptoms, that is characteristic for PD and differs from that in depressed patients without PD. Method: We compared the individual depressive symptoms of 145 non‐demented depressed patients with PD and 100 depressed patients without PD by comparing item scores on the Montgomery‐Åsberg Depression Rating Scale by way of MANCOVA. Results: The severity of depression and the level of cognitive functioning in depressed PD patients were comparable with that of depressed control subjects. However, patients with PD showed significant less reported sadness, less anhedonia, less feelings of guilt and, slightly less loss of energy, but more concentration problems than depressed control subjects. Conclusion: The profile of depressive symptoms in PD differs from that in depressed subjects without PD. This finding is important for the conceptualisation and clinical diagnosis of depression in PD. Copyright © 2006 John Wiley & Sons, Ltd.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Uwe Ehrt</name><affiliations><json:string>Section of Geriatric Psychiatry, Stavanger University Hospital, Norway</json:string></affiliations></json:item><json:item><name>Kolbjørn Brønnick</name><affiliations><json:string>Section of Geriatric Psychiatry, Stavanger University Hospital, Norway</json:string></affiliations></json:item><json:item><name>Albert F. G. Leentjens</name><affiliations><json:string>Department of Psychiatry, Maastricht University Hospital, The Netherlands</json:string></affiliations></json:item><json:item><name>Jan Petter Larsen</name><affiliations><json:string>Department of Neurology, Stavanger University Hospital, Norway</json:string><json:string>Norwegian Centre for Movement Disorders, Stavanger, Norway</json:string></affiliations></json:item><json:item><name>Dag Aarsland</name><affiliations><json:string>Section of Geriatric Psychiatry, Stavanger University Hospital, Norway</json:string><json:string>School of Medicine, University of Bergen, Norway</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Parkinson's disease</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>depression</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>symptom profile</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>neuropsychiatry</value></json:item></subject><articleId><json:string>GPS1456</json:string></articleId><language><json:string>eng</json:string></language><abstract>Objective: Depression is a common neuropsychiatric syndrome in Parkinson's disease (PD), and may be etiologically related to the neurochemical changes accompanying this disease. It is still unclear whether the disturbances of neurotransmitter activities lead to a specific profile of depressive symptoms, that is characteristic for PD and differs from that in depressed patients without PD. Method: We compared the individual depressive symptoms of 145 non‐demented depressed patients with PD and 100 depressed patients without PD by comparing item scores on the Montgomery‐Åsberg Depression Rating Scale by way of MANCOVA. Results: The severity of depression and the level of cognitive functioning in depressed PD patients were comparable with that of depressed control subjects. However, patients with PD showed significant less reported sadness, less anhedonia, less feelings of guilt and, slightly less loss of energy, but more concentration problems than depressed control subjects. Conclusion: The profile of depressive symptoms in PD differs from that in depressed subjects without PD. This finding is important for the conceptualisation and clinical diagnosis of depression in PD. 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J. Geriat. Psychiatry</title><idno type="pISSN">0885-6230</idno><idno type="eISSN">1099-1166</idno><idno type="DOI">10.1002/(ISSN)1099-1166</idno><imprint><publisher>John Wiley & Sons, Ltd.</publisher><pubPlace>Chichester, UK</pubPlace><date type="published" when="2006-03"></date><biblScope unit="volume">21</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="252">252</biblScope><biblScope unit="page" to="258">258</biblScope></imprint></monogr><idno type="istex">CB8596FF1264CC9706FA7D3D3FCEFAB7189DAA55</idno><idno type="DOI">10.1002/gps.1456</idno><idno type="ArticleID">GPS1456</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2006</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Objective: Depression is a common neuropsychiatric syndrome in Parkinson's disease (PD), and may be etiologically related to the neurochemical changes accompanying this disease. It is still unclear whether the disturbances of neurotransmitter activities lead to a specific profile of depressive symptoms, that is characteristic for PD and differs from that in depressed patients without PD. Method: We compared the individual depressive symptoms of 145 non‐demented depressed patients with PD and 100 depressed patients without PD by comparing item scores on the Montgomery‐Åsberg Depression Rating Scale by way of MANCOVA. Results: The severity of depression and the level of cognitive functioning in depressed PD patients were comparable with that of depressed control subjects. However, patients with PD showed significant less reported sadness, less anhedonia, less feelings of guilt and, slightly less loss of energy, but more concentration problems than depressed control subjects. Conclusion: The profile of depressive symptoms in PD differs from that in depressed subjects without PD. This finding is important for the conceptualisation and clinical diagnosis of depression in PD. Copyright © 2006 John Wiley & Sons, Ltd.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>Parkinson's disease</term></item><item><term>depression</term></item><item><term>symptom profile</term></item><item><term>neuropsychiatry</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>article category</head><item><term>Research Article</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2005-05-26">Received</change><change when="2005-08-22">Registration</change><change when="2006-03">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/CB8596FF1264CC9706FA7D3D3FCEFAB7189DAA55/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>John Wiley & Sons, Ltd.</publisherName><publisherLoc>Chichester, UK</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1099-1166</doi><issn type="print">0885-6230</issn><issn type="electronic">1099-1166</issn><idGroup><id type="product" value="GPS"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY">International Journal of Geriatric Psychiatry</title><title type="subtitle">A journal of the psychiatry of late life and allied sciences</title><title type="short">Int. 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G.</givenNames><familyName>Leentjens</familyName></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af3 #af5"><personName><givenNames>Jan Petter</givenNames><familyName>Larsen</familyName></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af1 #af4" corresponding="yes"><personName><givenNames>Dag</givenNames><familyName>Aarsland</familyName></personName><contactDetails><email>uehr@sir.no</email></contactDetails></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="NO" type="organization"><unparsedAffiliation>Section of Geriatric Psychiatry, Stavanger University Hospital, Norway</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="NL" type="organization"><unparsedAffiliation>Department of Psychiatry, Maastricht University Hospital, The Netherlands</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="NO" type="organization"><unparsedAffiliation>Department of Neurology, Stavanger University Hospital, Norway</unparsedAffiliation></affiliation><affiliation xml:id="af4" countryCode="NO" type="organization"><unparsedAffiliation>School of Medicine, University of Bergen, Norway</unparsedAffiliation></affiliation><affiliation xml:id="af5" countryCode="NO" type="organization"><unparsedAffiliation>Norwegian Centre for Movement Disorders, Stavanger, Norway</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">Parkinson's disease</keyword><keyword xml:id="kwd2">depression</keyword><keyword xml:id="kwd3">symptom profile</keyword><keyword xml:id="kwd4">neuropsychiatry</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><section xml:id="abs1-1"><title type="main">Objective</title><p>Depression is a common neuropsychiatric syndrome in Parkinson's disease (PD), and may be etiologically related to the neurochemical changes accompanying this disease. It is still unclear whether the disturbances of neurotransmitter activities lead to a specific profile of depressive symptoms, that is characteristic for PD and differs from that in depressed patients without PD.</p></section><section xml:id="abs1-2"><title type="main">Method</title><p>We compared the individual depressive symptoms of 145 non‐demented depressed patients with PD and 100 depressed patients without PD by comparing item scores on the Montgomery‐Åsberg Depression Rating Scale by way of MANCOVA.</p></section><section xml:id="abs1-3"><title type="main">Results</title><p>The severity of depression and the level of cognitive functioning in depressed PD patients were comparable with that of depressed control subjects. However, patients with PD showed significant less reported sadness, less anhedonia, less feelings of guilt and, slightly less loss of energy, but more concentration problems than depressed control subjects.</p></section><section xml:id="abs1-4"><title type="main">Conclusion</title><p>The profile of depressive symptoms in PD differs from that in depressed subjects without PD. This finding is important for the conceptualisation and clinical diagnosis of depression in PD. Copyright © 2006 John Wiley & Sons, Ltd.</p></section></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Depressive symptom profile in Parkinson's disease: a comparison with depression in elderly patients without Parkinson's disease</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>DEPRESSIVE SYMPTOM PROFILE IN PARKINSON'S DISEASE</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Depressive symptom profile in Parkinson's disease: a comparison with depression in elderly patients without Parkinson's disease</title></titleInfo><name type="personal"><namePart type="given">Uwe</namePart><namePart type="family">Ehrt</namePart><affiliation>Section of Geriatric Psychiatry, Stavanger University Hospital, Norway</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Kolbjørn</namePart><namePart type="family">Brønnick</namePart><affiliation>Section of Geriatric Psychiatry, Stavanger University Hospital, Norway</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Albert F. G.</namePart><namePart type="family">Leentjens</namePart><affiliation>Department of Psychiatry, Maastricht University Hospital, The Netherlands</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jan Petter</namePart><namePart type="family">Larsen</namePart><affiliation>Department of Neurology, Stavanger University Hospital, Norway</affiliation><affiliation>Norwegian Centre for Movement Disorders, Stavanger, Norway</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Dag</namePart><namePart type="family">Aarsland</namePart><affiliation>Section of Geriatric Psychiatry, Stavanger University Hospital, Norway</affiliation><affiliation>School of Medicine, University of Bergen, Norway</affiliation><description>Correspondence: Stavanger University Hospital, Psychiatric Clinic, PO Box 1163, Hillevåg, 4095 Stavanger, Norway.</description><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>John Wiley & Sons, Ltd.</publisher><place><placeTerm type="text">Chichester, UK</placeTerm></place><dateIssued encoding="w3cdtf">2006-03</dateIssued><dateCaptured encoding="w3cdtf">2005-05-26</dateCaptured><dateValid encoding="w3cdtf">2005-08-22</dateValid><copyrightDate encoding="w3cdtf">2006</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="tables">2</extent><extent unit="references">40</extent></physicalDescription><abstract lang="en">Objective: Depression is a common neuropsychiatric syndrome in Parkinson's disease (PD), and may be etiologically related to the neurochemical changes accompanying this disease. It is still unclear whether the disturbances of neurotransmitter activities lead to a specific profile of depressive symptoms, that is characteristic for PD and differs from that in depressed patients without PD. Method: We compared the individual depressive symptoms of 145 non‐demented depressed patients with PD and 100 depressed patients without PD by comparing item scores on the Montgomery‐Åsberg Depression Rating Scale by way of MANCOVA. Results: The severity of depression and the level of cognitive functioning in depressed PD patients were comparable with that of depressed control subjects. However, patients with PD showed significant less reported sadness, less anhedonia, less feelings of guilt and, slightly less loss of energy, but more concentration problems than depressed control subjects. Conclusion: The profile of depressive symptoms in PD differs from that in depressed subjects without PD. This finding is important for the conceptualisation and clinical diagnosis of depression in PD. Copyright © 2006 John Wiley & Sons, Ltd.</abstract><subject lang="en"><genre>Keywords</genre><topic>Parkinson's disease</topic><topic>depression</topic><topic>symptom profile</topic><topic>neuropsychiatry</topic></subject><relatedItem type="host"><titleInfo><title>International Journal of Geriatric Psychiatry</title><subTitle>A journal of the psychiatry of late life and allied sciences</subTitle></titleInfo><titleInfo type="abbreviated"><title>Int. J. Geriat. Psychiatry</title></titleInfo><genre type="Journal">journal</genre><subject><genre>article category</genre><topic>Research Article</topic></subject><identifier type="ISSN">0885-6230</identifier><identifier type="eISSN">1099-1166</identifier><identifier type="DOI">10.1002/(ISSN)1099-1166</identifier><identifier type="PublisherID">GPS</identifier><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>21</number></detail><detail type="issue"><caption>no.</caption><number>3</number></detail><extent unit="pages"><start>252</start><end>258</end><total>7</total></extent></part></relatedItem><identifier type="istex">CB8596FF1264CC9706FA7D3D3FCEFAB7189DAA55</identifier><identifier type="DOI">10.1002/gps.1456</identifier><identifier type="ArticleID">GPS1456</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2006 John Wiley & Sons, Ltd.</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>John Wiley & Sons, Ltd.</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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